Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4860425 | 0.99 | ACHE (0.46) | ACHEBCHESIGMAR1CYP11B1CYP11B2 | |
| SCHEMBL13987254 | 0.99 | ACHE (0.47) | ACHEBCHESIGMAR1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL4857379 | 0.98 | ACHE (0.47) | ACHEBCHESIGMAR1CYP11B1CYP11B2 | |
| SCHEMBL4860509 | 0.91 | ACHE (0.47) | ACHEBCHECYP11B1CYP11B2CYP19A1 | |
| SCHEMBL4858814 | 0.90 | ACHE (0.47) | ACHECYP11B1CYP11B2CYP19A1 | |
| SCHEMBL13987286 | 0.88 | ACHE (0.56) | ACHESIGMAR1DRD2DRD3KCNH2 | |
| SCHEMBL13987291 | 0.88 | HTR1A (0.49) | ACHESIGMAR1CYP11B1CYP11B2DRD2 | |
| SCHEMBL13987297 | 0.88 | ACHE (0.50) | ACHESIGMAR1CYP11B1CYP11B2DRD2 | |
| Hydrochloric Acid SCHEMBL4862249 | 0.87 | ACHE (0.55) | ACHESIGMAR1DRD2DRD3KCNH2 | |
| SCHEMBL4855221 | 0.87 | ACHE (0.44) | ACHEBCHECYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |