Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987309 | 0.99 | NPC1 (0.49) | NPC1TTRACHESIGMAR1BCHE | |
| SCHEMBL13987341 | 0.96 | ACHE (0.47) | NPC1TTRACHESIGMAR1 | |
| SCHEMBL13987328 | 0.95 | ACHE (0.47) | NPC1TTRACHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL4912555 | 0.94 | ACHE (0.47) | NPC1TTRACHESIGMAR1 | |
| SCHEMBL6035326 | 0.91 | ACHE (0.49) | NPC1TTRACHEBCHE | |
| SCHEMBL13987287 | 0.90 | TDP1 (0.47) | ACHESIGMAR1BCHECHRM2CHRM1 | |
| SCHEMBL6034266 | 0.90 | NPC1 (0.46) | NPC1TTRACHEBCHERAB9A | |
| Hydrochloric Acid SCHEMBL4858639 | 0.90 | ACHE (0.48) | NPC1TTRACHEBCHE | |
| SCHEMBL6034769 | 0.90 | ACHE (0.47) | NPC1TTRACHEBCHERAB9A | |
| SCHEMBL4860303 | 0.90 | NPC1 (0.47) | NPC1TTRACHERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |