Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987328 | 0.99 | ACHE (0.47) | ACHESIGMAR1NPC1TTR | |
| Hydrochloric Acid SCHEMBL4912555 | 0.98 | ACHE (0.47) | ACHESIGMAR1NPC1TTR | |
| SCHEMBL13987315 | 0.96 | NPC1 (0.48) | ACHESIGMAR1NPC1TTR | |
| SCHEMBL13987287 | 0.95 | TDP1 (0.47) | ACHESIGMAR1 | |
| SCHEMBL13987309 | 0.95 | NPC1 (0.49) | ACHESIGMAR1NPC1TTR | |
| Hydrochloric Acid SCHEMBL4851823 | 0.94 | TDP1 (0.46) | ACHESIGMAR1 | |
| SCHEMBL13987253 | 0.94 | TDP1 (0.47) | ACHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL4860554 | 0.93 | TDP1 (0.47) | ACHESIGMAR1 | |
| SCHEMBL13987349 | 0.91 | ACHE (0.48) | ACHE | |
| SCHEMBL13987350 | 0.90 | ACHE (0.44) | ACHENPC1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |