Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987358 | 0.99 | HTR1A (0.50) | HTR1ADRD2HTR2AHRH1DRD3 | |
| Hydrochloric Acid SCHEMBL4851902 | 0.99 | HTR1A (0.50) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL13987684 | 0.97 | HTR1A (0.54) | HTR1ADRD2HTR2AHRH1DRD3 | |
| Hydrochloric Acid SCHEMBL4861361 | 0.96 | HTR1A (0.53) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL4858462 | 0.87 | HTR1A (0.56) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL13987356 | 0.86 | HTR1A (0.55) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL13987691 | 0.84 | HTR1A (0.60) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL13987685 | 0.83 | ALDH1A1 (0.55) | DRD3 | |
| Hydrochloric Acid SCHEMBL4859353 | 0.83 | HTR1A (0.61) | HTR1ADRD2HTR2AHRH1DRD3 | |
| Hydrochloric Acid SCHEMBL4862233 | 0.82 | ALDH1A1 (0.57) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |