Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4863003 | 0.99 | ACHE (0.47) | ACHENPC1TTRHTR1ADRD2 | |
| SCHEMBL13987248 | 0.90 | ACHE (0.49) | ACHENPC1TTR | |
| Hydrochloric Acid SCHEMBL4863292 | 0.89 | ACHE (0.49) | ACHENPC1TTR | |
| SCHEMBL13987282 | 0.89 | ACHE (0.49) | ACHENPC1TTR | |
| Hydrochloric Acid SCHEMBL4862894 | 0.88 | ACHE (0.48) | ACHENPC1TTR | |
| SCHEMBL13987454 | 0.88 | ACHE (0.52) | ACHENPC1TTRHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL4862482 | 0.87 | ACHE (0.51) | ACHENPC1TTRHTR1ADRD2 | |
| SCHEMBL13987453 | 0.85 | ACHE (0.48) | ACHENPC1TTRHTR1ADRD2 | |
| SCHEMBL4859252 | 0.85 | ACHE (0.57) | ACHEHTR1ADRD2DRD1HTR2A | |
| Hydrochloric Acid SCHEMBL4853188 | 0.85 | ACHE (0.48) | ACHENPC1TTRHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |