Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4857194 | 0.99 | HTR1A (0.56) | ACHEHTR1ADRD2HTR2AHRH1 | |
| SCHEMBL13987697 | 0.99 | HTR1A (0.56) | ACHEHTR1ADRD2HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL4858434 | 0.98 | HTR1A (0.55) | ACHEHTR1ADRD2HTR2AHRH1 | |
| SCHEMBL13987649 | 0.95 | HTR1A (0.61) | ACHEHTR1ADRD2HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL4851982 | 0.94 | HTR1A (0.60) | ACHEHTR1ADRD2HTR2AHRH1 | |
| SCHEMBL13987359 | 0.92 | ACHE (0.56) | ACHEHTR1ADRD2HTR2AHRH1 | |
| SCHEMBL4858462 | 0.90 | HTR1A (0.56) | ACHEHTR1ADRD2HTR2AHRH1 | |
| SCHEMBL13987356 | 0.89 | HTR1A (0.55) | ACHEHTR1ADRD2HTR2AHRH1 | |
| SCHEMBL13987691 | 0.86 | HTR1A (0.60) | ACHEHTR1ADRD2HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL4859353 | 0.85 | HTR1A (0.61) | ACHEHTR1ADRD2HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |