SCHEMBL13989196

SCHEMBL13989196

O=C(CCN1CCCC1)Nc1ccc2c(NCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 20/20 1.00
▸ POT1 Q9NUX5 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13989197 0.95 TERT (1.00) TERTPOT1
SCHEMBL13989194 0.88 TERT (0.85) TERTPOT1
SCHEMBL13989192 0.84 TERT (1.00) TERTPOT1
SCHEMBL31237593 0.84 TERT (0.78) TERTPOT1
SCHEMBL13989208 0.84 TERT (0.77) TERTPOT1
SCHEMBL13989209 0.84 TERT (0.78) TERTPOT1
SCHEMBL13989193 0.83 TERT (0.80) TERTPOT1
SCHEMBL13989200 0.83 TERT (1.00) TERTPOT1
SCHEMBL13989195 0.83 TERT (1.00) TERTPOT1
SCHEMBL13989205 0.83 TERT (1.00) TERTPOT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080319001-A1 Cancer Treatment Using Specific 3,6,9-Substituted Acridines CANCER RESEARCH TECHNOLOGY LTD (GB) 2008-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319001-A1 Cancer Treatment Using Specific 3,6,9-Substituted Acridines FOLR1, TP53, FOLR2 TERT 181/4885POT1 2293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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