SCHEMBL13989331

SCHEMBL13989331

C[n+]1cccc(Cn2ncc(N)c2N)c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.49
ALDH1A1 P00352 3/20 0.40
CHRNA7 P36544 1/20 0.35
PKM P14618 1/20 0.35
RECQL P46063 1/20 0.34
FDPS P14324 1/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
HDAC8 Q9BY41 3/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NNMT P40261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5201212 0.98 TSHR (0.48) TSHRALDH1A1CHRNA7PKMRECQL
Hydrochloric Acid SCHEMBL4863978 0.88 TSHR (0.42) TSHRALDH1A1PKMFDPSNPC1
SCHEMBL13989333 0.83 TSHR (0.49) TSHRALDH1A1PKMRECQLNPC1
SCHEMBL16366778 0.81 TSHR (0.43) TSHRALDH1A1CHRNA7PKMRECQL
SCHEMBL144813 0.79 TSHR (0.69) TSHRALDH1A1RECQLPOLBGAA
SCHEMBL16367025 0.78 TSHR (0.46) TSHRALDH1A1CHRNA7PKMRECQL
SCHEMBL6003862 0.77 TSHR (0.53) TSHRALDH1A1PKMRECQLLMNA
Hydrochloric Acid SCHEMBL16325081 0.77 TSHR (0.45) TSHRALDH1A1CHRNA7PKMRECQL
Hydrochloric Acid SCHEMBL16325079 0.77 TSHR (0.45) TSHRALDH1A1CHRNA7PKMRECQL
SCHEMBL3254682 0.76 TSHR (0.55) TSHRALDH1A1PKMRECQLNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7462204-B2 Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds WELLA AG (DE) 2008-12-09 US disclosed
US-20070056120-A1 Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070056120-A1 Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds KRT18, DSP, TUBA4A TSHR 4756/4885ALDH1A1 978/4885CHRNA7 1572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.