TUBA4A

Tubulin alpha-4A chain · P68366 · TUBA4A on Sugi Atlas →

133,555 patent compounds predicted against TUBA4A, 84,683 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Curacin A Curacin A (SCHEMBL61304) 1.00 20/20
Vintriptol Vintriptol (SCHEMBL93959) 1.00 15/20
Vindesine Vindesine (SCHEMBL4420) 0.85 13/20
Vindesine Vindesine (SCHEMBL4421) 0.85 13/20
Vindesine Vindesine (SCHEMBL4285) 0.85 12/20
SCHEMBL147173 SCHEMBL147173 0.50 12/20
SCHEMBL147174 SCHEMBL147174 0.50 12/20
Combretastatin Combretastatin (SCHEMBL19955) 1.00 9/20
Combretastatin Combretastatin (SCHEMBL19956) 1.00 9/20
SCHEMBL118593 SCHEMBL118593 0.69 9/20
Centaureidin Centaureidin (SCHEMBL9953) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43160) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43161) 1.00 8/20
SCHEMBL68067 SCHEMBL68067 0.62 8/20
Fosbretabulin Fosbretabulin (SCHEMBL66079) 0.61 8/20
Vinorelbine Vinorelbine (SCHEMBL4765) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18945) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18946) 1.00 7/20
Levofloxacin Anhydrous Levofloxacin Anhydrous (SCHEMBL15397) 0.98 7/20
Ofloxacin Ofloxacin (SCHEMBL24373) 0.98 7/20

Clinical trials — most relevant to TUBA4A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparative Analysis of the Efficacies in Neoadjuvant Chemotherapy of Breast Cancer PHASE3COMPLETED
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Neoadjuvant Paclitaxel Plus Epirubicin Versus Vinorelbine Plus Epirubicin in Breast Cancer With TEKT4 Variations PHASE2COMPLETED
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer PHASE2COMPLETED
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer PHASE2UNKNOWN
Therapy With Docetaxel and ZD1839 for Patients Who Have Advanced Breast Cancer PHASE2COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Treating Patients With Advanced Solid Tumors, Breast Cancer or Recurrent Ovarian Cancer PHASE1COMPLETED
Exploratory Evaluation of [11C]MPC6827 EARLY_PHASE1COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children nanCOMPLETED
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting nanUNKNOWN
Importance of the Microtubule Cytoskeleton in Oocyte Competence nanCOMPLETED
Early Detection and Characterization of Primary Ciliary Dyskinesia nanUNKNOWN
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Effect of Low Dose of Colchicine on Platelet Reactivity nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Evaluation of a Novel PET Radioligand to Image OGA nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
WGS of Korean Idiopathic Bronchiectasis nanUNKNOWN
Thermal Spa Treatment and Improvement of Primary Ciliary Dyskinesia nanRECRUITING
Myotubular Myopathy Genetic Testing Study nanCOMPLETED
Biomarkers and Validation of Selected Outcome Measures (CMTBiomarker) nanCOMPLETED
NGS Panel of Incomplete Forms of Ocular Albinism nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TUBA4A binder may also engage these)

ProteinNameSimilarity
P02552 1.000 P02552 →
P68369 1.000 P68369 →
Q5XIF6 1.000 Q5XIF6 →
P68368 1.000 P68368 →
P68367 1.000 P68367 →
Q91060 1.000 Q91060 →
P68360 1.000 P68360 →
Q52PV9 1.000 Q52PV9 →
Q2HJB8 1.000 Q2HJB8 →
P06604 1.000 P06604 →
A5A6J1 1.000 A5A6J1 →
P81948 1.000 P81948 →
P68370 1.000 P68370 →
Q2HJ86 1.000 Q2HJ86 →
P0DPH8 1.000 P0DPH8 →
Q94572 1.000 Q94572 →
P02550 1.000 P02550 →
P34690 1.000 P34690 →
Q6AYZ1 1.000 Q6AYZ1 →
Q28IX8 1.000 Q28IX8 →
P68373 1.000 P68373 →
Q6AY56 1.000 Q6AY56 →
TUBA8 Tubulin alpha-8 chain 1.000 landscape →
P30436 1.000 P30436 →
P68361 1.000 P68361 →
Q06331 1.000 Q06331 →
P91910 1.000 P91910 →
P18288 1.000 P18288 →
Q68FR8 1.000 Q68FR8 →
Q25008 1.000 Q25008 →