Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061054 | 0.89 | AR (0.51) | AR | |
| SCHEMBL5942331 | 0.89 | AR (0.51) | AR | |
| SCHEMBL3184244 | 0.89 | AR (0.51) | AR | |
| SCHEMBL13482168 | 0.89 | AR (0.51) | AR | |
| SCHEMBL13482225 | 0.87 | AR (0.41) | AR | |
| SCHEMBL13482414 | 0.86 | AR (0.38) | AR | |
| SCHEMBL13989372 | 0.84 | ALDH1A1 (0.37) | ARCRBNRAB9A | |
| SCHEMBL13889345 | 0.82 | AR (0.48) | AR | |
| SCHEMBL13889354 | 0.81 | AR (0.47) | AR | |
| SCHEMBL13889766 | 0.80 | AR (0.46) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |