Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628462 | 0.91 | CA2 (0.37) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL2932570 | 0.90 | MAPT (0.42) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL2927954 | 0.85 | MAPT (0.39) | KMT2AALDH1A1MAPTCXCR2PBRM1 | |
| SCHEMBL1115893 | 0.83 | MAPT (0.42) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL2924883 | 0.80 | MAPT (0.44) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL2931556 | 0.78 | MAPT (0.39) | MEN1KMT2AMAPTFABP3FABP4 | |
| SCHEMBL1116247 | 0.78 | MAPT (0.44) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL12856603 | 0.78 | MAPT (0.46) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL2925394 | 0.77 | MAPT (0.42) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL2925195 | 0.77 | NPC1 (0.40) | KMT2AMAPTCXCR2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306064-A1 | Benzimidazole Derivatives | BROWN LYNDON NIGEL | 2008-12-11 | — | — | US | disclosed |
| US-20080306064-A1 | Benzimidazole Derivatives | BROWN LYNDON NIGEL | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306064-A1 | Benzimidazole Derivatives | PPARG, PPARD, BRD4 | MEN1 4765/4885KMT2A 3456/4885LMNA 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.