SCHEMBL139911

SCHEMBL139911

CCOP(=O)(COS(=O)(=O)c1ccc(C)cc1)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
STAT3 P40763 1/20 0.39
ALDH1A1 P00352 4/20 0.39
GAA P10253 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 2/20 0.38
MEN1 O00255 1/20 0.38
VDR P11473 1/20 0.36
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA5B Q9Y2D0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9302318 0.87 CA12 (0.39) CA12CA1CA2CA9STAT3
SCHEMBL4206457 0.86 CA12 (0.40) CA12CA1CA2CA9STAT3
SCHEMBL118162 0.86 CA12 (0.42) CA12CA1CA2CA9ALDH1A1
SCHEMBL28775410 0.85 LMNA (0.43) CA12CA1CA2CA9ALDH1A1
SCHEMBL23703121 0.84 CA12 (0.42) CA12CA1CA2CA9STAT3
Pyridine SCHEMBL6266454 0.84 STAT3 (0.35) CA12CA1CA2CA9STAT3
SCHEMBL8871679 0.83 STAT3 (0.43) CA12CA1CA2CA9STAT3
SCHEMBL1393935 0.83 TSHR (0.44) CA12CA1CA2CA9STAT3
SCHEMBL29667787 0.82 CA2 (0.51) CA12CA1CA2CA9ALDH1A1
SCHEMBL9063891 0.82 CA12 (0.38) CA12CA1CA2CA9STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120022913-A Method for using high-stability copper-based catalyst in hydrochlorination of acetylene 中盐吉兰泰氯碱化工有限公司 2025-05-23 CN claimed
CN-119708059-A Post-production treatment method for tenofovir 石家庄龙泽制药股份有限公司 2025-03-28 CN claimed
CN-115974921-B Synthetic tenor Fuwei method 浙江嘉化新材料有限公司 2025-03-14 CN claimed
CN-118652277-A Preparation method of compound for treating cancer diseases 成都工业学院 2024-09-17 CN claimed
CN-118530274-A Preparation method of diethyl p-toluenesulfonyloxy methylphosphonate 江西永通科技股份有限公司 2024-08-23 CN claimed
CN-116854735-A Synthesis method of tenofovir 广西奕安泰药业有限公司 2023-10-10 CN claimed
CN-115974921-A Method for synthesizing tenofovir 浙江嘉化新材料有限公司 2023-04-18 CN claimed
CN-114843597-A Flame-retardant self-repairing quasi-solid polymer electrolyte and preparation method thereof 河北师范大学 2022-08-02 CN claimed
CN-215811163-U Raw material weighing device is used in preparation of p toluene sulfonyl oxygen methyl phosphonic acid diethyl ester 济南立德医药技术有限公司 2022-02-11 CN claimed
CN-215464416-U Reaction kettle for preparing diethyl p-toluenesulfonyloxymethylphosphonate 济南立德医药技术有限公司 2022-01-11 CN claimed
CN-108178772-B Preparation method of tenofovir disoproxil fumarate intermediate 上海博悦生物科技有限公司 2020-01-21 CN claimed
CN-108627647-A A kind of detection of posttranslational modification proteomics and quantitative approach 四川大学 2018-10-09 CN claimed
CN-106046055-A R-9-(2-phosphonomethoxy propyl)-adenine monohydrate crystals, preparation thereof and preparation of tenofovir disoproxil fumarate 湖北丽益医药科技有限公司 2016-10-26 CN claimed
CN-103641858-B A kind of tenofovir disoproxil fumarate and preparation method thereof HUNAN QIANJIN XIANGJIANG PHARMACEUTICAL CO., LTD. (CN) 2016-01-20 CN claimed
US-8759515-B2 Process for the preparation of tenofovir disoproxil fumarate MYLAN LABORATORIES LIMITED (IN) 2014-06-24 US claimed
CN-103641858-A Tenofovir disoproxil fumarate and preparation method thereof HUNAN QIANJIN XIANGJIANG PHARM CO LTD 2014-03-19 CN claimed
EP-2545063-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL FUMARATE Matrix Laboratories Ltd (IN) 2013-01-16 EP claimed
US-20130005969-A1 PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL FUMARATE MYLAN LABORATORIES LIMITED (IN) 2013-01-03 US claimed
WO-2011111074-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL FUMARATE MATRIX LABORATORIES LTD (IN) 2011-09-15 WO claimed
EP-1256585-A1 Process fot preparing 9-(2-(diethylphosphonomethoxy)ethyl)-adenine GILEAD SCIENCES, INC. (US) 2002-11-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130005969-A1 PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL FUMARATE TYMP, PNP, MTAP CA12 2586/4885CA1 2361/4885CA2 1011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.