Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13991949 | 0.82 | ALDH1A1 (0.38) | CYP1A2CYP2C9KDM4E | |
| SCHEMBL4123645 | 0.69 | EEF2K (0.75) | EEF2KCYP1A2CYP2C9KDM4E | |
| SCHEMBL13991924 | 0.64 | ALDH1A1 (0.36) | KDM4E | |
| SCHEMBL30174195 | 0.58 | EEF2K (0.41) | EEF2KCYP2C9KDM4E | |
| SCHEMBL14317334 | 0.56 | NUDT1 (0.41) | KDM4E | |
| SCHEMBL9684673 | 0.55 | KDM4E (0.49) | EEF2KCYP1A2CYP2C9KDM4E | |
| SCHEMBL7916071 | 0.54 | TSHR (0.44) | CYP1A2CYP2C9KDM4E | |
| SCHEMBL15598418 | 0.54 | KDM4E (0.52) | CYP1A2CYP2C9KDM4E | |
| SCHEMBL7917747 | 0.54 | TSHR (0.44) | CYP1A2CYP2C9KDM4E | |
| SCHEMBL13925351 | 0.52 | TSHR (0.42) | CYP1A2CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465742-B2 | Heterocyclic compounds having anti-HBV activity | VRX HOLDCO LLC | 2008-12-16 | — | — | US | disclosed |