Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396044 | 0.88 | TAAR1 (0.49) | IFNAR1LMNARECQLSMN1; SMN2HTR2A | |
| SCHEMBL1399201 | 0.86 | IFNAR1 (0.41) | IFNAR1HTR2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1399400 | 0.86 | IFNAR1 (0.58) | IFNAR1LMNARECQLSMN1; SMN2SLC6A4 | |
| SCHEMBL1399380 | 0.86 | IFNAR1 (0.58) | IFNAR1LMNARECQLSMN1; SMN2HTR2A | |
| SCHEMBL1399276 | 0.84 | PCSK9 (0.46) | IFNAR1HTR2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1399271 | 0.82 | IFNAR1 (0.54) | IFNAR1LMNARECQLSMN1; SMN2HTR2A | |
| SCHEMBL1399178 | 0.82 | LMNA (0.56) | LMNASMN1; SMN2SLC6A4SLC6A2PRMT1 | |
| SCHEMBL1399164 | 0.81 | HTR2A (0.63) | SMN1; SMN2HTR2ASLC6A4DYRK1AAR | |
| SCHEMBL1399315 | 0.81 | IFNAR1 (0.51) | IFNAR1LMNARECQLSMN1; SMN2SLC6A4 | |
| SCHEMBL1399362 | 0.80 | IFNAR1 (0.60) | IFNAR1LMNARECQLSMN1; SMN2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |