Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390799 | 0.88 | MTNR1A (0.49) | IFNAR1KMT2AHTR2ALMNAHTR6 | |
| SCHEMBL1399196 | 0.87 | IDO1 (0.48) | IFNAR1HTR2AHTR6DYRK1AMTNR1A | |
| SCHEMBL1399179 | 0.85 | IDO1 (0.48) | IFNAR1HTR2AHTR6DYRK1AMTNR1A | |
| SCHEMBL1399259 | 0.85 | IDO1 (0.48) | IFNAR1HTR2AHTR6DYRK1AMTNR1A | |
| SCHEMBL1399266 | 0.84 | KMT2A (0.49) | IFNAR1KMT2AMEN1POLBLMNA | |
| SCHEMBL1399400 | 0.84 | IFNAR1 (0.58) | IFNAR1KMT2AMEN1POLBLMNA | |
| SCHEMBL1399380 | 0.84 | IFNAR1 (0.58) | IFNAR1KMT2AMEN1POLBHTR2A | |
| SCHEMBL1399218 | 0.83 | HTR2A (0.66) | KMT2AHTR2ASMN1; SMN2HTR6DYRK1A | |
| SCHEMBL1399180 | 0.83 | LMNA (0.53) | HTR2ALMNASMN1; SMN2HTR6DYRK1A | |
| SCHEMBL1399267 | 0.82 | IFNAR1 (0.57) | IFNAR1KMT2AMEN1POLBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |