Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399375 | 0.90 | PTGS1 (0.47) | PTGS2PTGS1KDM4ETUBB4ATUBB | |
| SCHEMBL1399228 | 0.86 | MPO (0.45) | PTGS2PTGS1MAPTKDM4ETUBB4A | |
| SCHEMBL1399484 | 0.85 | PTGS1 (0.45) | PTGS2PTGS1KDM4EMAPK1KMT2A | |
| SCHEMBL1399328 | 0.83 | MAPT (0.45) | MAPTKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL1399319 | 0.83 | PTGS2 (0.46) | PTGS2PTGS1MAPTKDM4ETUBB4A | |
| SCHEMBL1399496 | 0.83 | IDO1 (0.44) | PTGS2PTGS1MAPTKDM4ETUBB4A | |
| SCHEMBL1399240 | 0.79 | MAPT (0.46) | MAPTKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL1399401 | 0.76 | IDO1 (0.44) | PTGS2PTGS1MAPTKDM4ETUBB4A | |
| SCHEMBL1399425 | 0.74 | HTR2A (0.49) | MAPTNPSR1KMT2ASMN1; SMN2HTR2A | |
| SCHEMBL4382124 | 0.74 | PTGS1 (0.41) | PTGS2PTGS1MAPTKDM4ETUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |