Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.53 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.45 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100058 | 0.97 | MGLL (0.49) | MGLLTRPC3TRPC7PRMT5SMN1; SMN2 | |
| SCHEMBL13158575 | 0.93 | MGLL (0.54) | MGLLTRPC3TRPC7SMN1; SMN2NPC1 | |
| SCHEMBL3109291 | 0.90 | MGLL (0.58) | MGLLTRPC3TRPC7PRMT5SMN1; SMN2 | |
| SCHEMBL3100073 | 0.89 | MDM2 (0.56) | MGLLTRPC3TRPC7PRMT5SMN1; SMN2 | |
| SCHEMBL3099562 | 0.88 | MGLL (0.56) | MGLLTRPC3TRPC7PRMT5SMN1; SMN2 | |
| SCHEMBL3100698 | 0.88 | MGLL (0.55) | MGLLTRPC3TRPC7PRMT5SMN1; SMN2 | |
| SCHEMBL3098084 | 0.86 | MGLL (0.55) | MGLLTRPC3TRPC7PRMT5SMN1; SMN2 | |
| SCHEMBL3096845 | 0.86 | MGLL (0.55) | MGLLTRPC3TRPC7PRMT5SMN1; SMN2 | |
| SCHEMBL3093698 | 0.86 | MGLL (0.55) | MGLLTRPC3TRPC7PRMT5SMN1; SMN2 | |
| SCHEMBL3103473 | 0.80 | MDM2 (0.42) | MGLLMDM2BCL2MCL1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009006-A1 | UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2008-12-31 | — | — | EP | disclosed |