Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.58 |
| ▸ | RPA1 | P27694 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.47 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099562 | 0.98 | MGLL (0.56) | MGLLRPA1GRIN2BTRPC3TRPC7 | |
| SCHEMBL3098084 | 0.97 | MGLL (0.55) | MGLLRPA1GRIN2BTRPC3TRPC7 | |
| SCHEMBL3096845 | 0.97 | MGLL (0.55) | MGLLRPA1GRIN2BTRPC3TRPC7 | |
| SCHEMBL3093698 | 0.97 | MGLL (0.55) | MGLLRPA1GRIN2BTRPC3TRPC7 | |
| SCHEMBL3100058 | 0.92 | MGLL (0.49) | MGLLGRIN2BTRPC3TRPC7SMN1; SMN2 | |
| SCHEMBL3100073 | 0.92 | MDM2 (0.56) | MGLLGRIN2BTRPC3TRPC7SMN1; SMN2 | |
| SCHEMBL3100698 | 0.91 | MGLL (0.55) | MGLLGRIN2BTRPC3TRPC7SMN1; SMN2 | |
| SCHEMBL13158575 | 0.91 | MGLL (0.54) | MGLLGRIN2BTRPC3TRPC7SMN1; SMN2 | |
| SCHEMBL13993243 | 0.90 | MGLL (0.53) | MGLLTRPC3TRPC7SMN1; SMN2NPC1 | |
| SCHEMBL3104950 | 0.86 | MGLL (0.50) | MGLLRPA1KCNJ6KCNJ3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2009006-A1 | UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2008-12-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | UROD, UTS2R, SLC14A1 | MGLL 1894/4885RPA1 4666/4885GRIN2B 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.