Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | BMX | P51813 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109886 | 0.87 | HTR2B (0.49) | HTR2BSMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL3099823 | 0.86 | HTT (0.59) | HTR2BMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL8576094 | 0.83 | MAPK14 (0.51) | HTR2BKITCSNK1A1CSNK1DRPS6KA3 | |
| SCHEMBL4026671 | 0.80 | MAPK11 (0.68) | MAPTKDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL3089253 | 0.79 | MAPK14 (0.62) | HTR2BSMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL6168935 | 0.78 | HTR2B (0.48) | HTR2BSMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL6227723 | 0.73 | BRAF (0.64) | CSNK1A1CSNK1DRPS6KA3MAPK13RAF1 | |
| SCHEMBL5438668 | 0.73 | MAPT (0.41) | SMN1; SMN2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL2636579 | 0.73 | HSD11B1 (0.61) | SMN1; SMN2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL4025331 | 0.73 | CSNK1A1 (0.67) | CSNK1A1CSNK1DRPS6KA3MAPK13RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009006-A1 | UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2008-12-31 | — | — | EP | disclosed |