Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.62 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.62 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.62 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.62 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.62 |
| ▸ | RAF1 | P04049 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584136 | 0.81 | MAPK14 (0.60) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL13993259 | 0.79 | HTR2B (0.53) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4585317 | 0.78 | MAPK14 (0.63) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL4024638 | 0.76 | MAPK11 (1.00) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL4587083 | 0.76 | MAPK11 (1.00) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL8113482 | 0.76 | MAPK14 (0.58) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL4586963 | 0.76 | MAPK14 (0.67) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL3109886 | 0.76 | HTR2B (0.49) | MEN1KMT2ANOX1CSNK1A1CSNK1D | |
| SCHEMBL3099823 | 0.75 | HTT (0.59) | MEN1KMT2AHTR2BALDH1A1HPGD | |
| SCHEMBL2755241 | 0.75 | MEN1 (0.51) | MEN1KMT2AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2009006-A1 | UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2008-12-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | UROD, UTS2R, SLC14A1 | MAPK14 985/4885MAPK13 1318/4885MAPK9 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.