SCHEMBL13993530

SCHEMBL13993530

CN(Cc1ccc(F)cc1)C(=O)C(NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(C)(C)C)cc3)ccc2c1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MTTP P55157 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1622842 1.00 MTTP (1.00) MTTP
SCHEMBL13495432 0.91 MTTP (0.84) MTTP
SCHEMBL3232241 0.91 MTTP (0.84) MTTP
SCHEMBL13996046 0.91 MTTP (0.89) MTTP
SCHEMBL3239404 0.91 MTTP (0.83) MTTP
SCHEMBL14046300 0.89 MTTP (0.79) MTTP
SCHEMBL1621570 0.87 MTTP (1.00) MTTP
SCHEMBL13495434 0.84 MTTP (0.72) MTTP
SCHEMBL14027938 0.84 MTTP (0.72) MTTP
SCHEMBL14027886 0.83 MTTP (0.71) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7468378-B2 Substituted quinoline compounds PFIZER INC. (US) 2008-12-23 US disclosed
US-7468378-B2 Substituted quinoline compounds PFIZER INC. (US) 2008-12-23 US disclosed
US-7393958-B2 Triamide-substituted heterobicyclic compounds PFIZER, INC. (US) 2008-07-01 US disclosed
US-7368573-B2 Triamide-substituted heterobicyclic compounds PFIZER INC. (US) 2008-05-06 US disclosed