SCHEMBL3239404

SCHEMBL3239404

COc1cccc(C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)c1-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MTTP P55157 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3232241 0.93 MTTP (0.84) MTTP
SCHEMBL13495432 0.93 MTTP (0.84) MTTP
SCHEMBL1622842 0.91 MTTP (1.00) MTTP
SCHEMBL13993530 0.91 MTTP (1.00) MTTP
SCHEMBL13495434 0.88 MTTP (0.72) MTTP
SCHEMBL14027988 0.83 MTTP (0.57) MTTP
SCHEMBL13996046 0.82 MTTP (0.89) MTTP
SCHEMBL14046300 0.81 MTTP (0.79) MTTP
SCHEMBL4986089 0.79 MTTP (0.53) MTTP
SCHEMBL1621570 0.79 MTTP (1.00) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010018547-A1 AMINOQUINOLINE COMPOUNDS PFIZER INC. (US) 2010-02-18 WO disclosed
WO-2010018547-A1 AMINOQUINOLINE COMPOUNDS PFIZER INC. (US) 2010-02-18 WO disclosed