Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399248 | 0.86 | IFNAR1 (0.50) | RECQLIFNAR1SMN1; SMN2TUBB4ATUBB | |
| SCHEMBL1399483 | 0.85 | IDO1 (0.64) | IFNAR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399348 | 0.85 | IDO1 (0.60) | RECQLIFNAR1SMN1; SMN2TUBB4ATUBB | |
| SCHEMBL1399539 | 0.85 | IDO1 (0.60) | KDM4EALDH1A1RECQLHPGDMAPT | |
| SCHEMBL1399382 | 0.85 | IDO1 (0.62) | IFNAR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399362 | 0.84 | IFNAR1 (0.60) | KDM4EALDH1A1RECQLMAPTMEN1 | |
| SCHEMBL1399503 | 0.83 | MEN1 (0.56) | KDM4EMAPTHTR2CMEN1CYP2D6 | |
| SCHEMBL1399413 | 0.82 | IFNAR1 (0.46) | KDM4EALDH1A1RECQLHPGDMAPT | |
| SCHEMBL1399343 | 0.81 | HTR2C (0.62) | KDM4EALDH1A1RECQLHPGDMAPT | |
| SCHEMBL3185285 | 0.81 | IFNAR1 (0.50) | KDM4EALDH1A1RECQLHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |