Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.60 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632176 | 0.90 | CHRNB2 (0.50) | IDO1IFNAR1GPR84SLC6A2SLC6A4 | |
| SCHEMBL1399248 | 0.86 | IFNAR1 (0.50) | IDO1IFNAR1TUBB4ATUBBTUBA3C | |
| SCHEMBL1399378 | 0.85 | KDM4E (0.53) | IDO1IFNAR1TUBB4ATUBBTUBA3C | |
| SCHEMBL1399382 | 0.85 | IDO1 (0.62) | IDO1IFNAR1GPR84TUBB4ATUBB | |
| SCHEMBL1399539 | 0.85 | IDO1 (0.60) | IDO1IFNAR1TUBB4ATUBBTUBA3C | |
| SCHEMBL1399483 | 0.85 | IDO1 (0.64) | IDO1IFNAR1GPR84TUBB4ATUBB | |
| SCHEMBL1399204 | 0.84 | IDO1 (0.54) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL1399362 | 0.84 | IFNAR1 (0.60) | IDO1IFNAR1GPR84TUBB4ATUBB | |
| SCHEMBL22802298 | 0.83 | IDO1 (0.61) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL31379805 | 0.83 | IDO1 (0.61) | IDO1GPR84TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |