Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.52 |
| ▸ | TUBB | P07437 | 2/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632657 | 0.91 | MEN1 (0.56) | MEN1POLBKMT2AGPR84HTR2A | |
| SCHEMBL1399264 | 0.85 | IDO1 (0.56) | MEN1KMT2AGPR84HTR2ATUBB4A | |
| SCHEMBL1399239 | 0.85 | IDO1 (0.59) | GPR84HTR2ATUBB4ATUBBTUBA3C | |
| SCHEMBL1399215 | 0.85 | IDO1 (0.59) | GPR84HTR2ATUBB4ATUBBTUBA3C | |
| SCHEMBL4632114 | 0.84 | IDO1 (0.51) | MEN1POLBKMT2ATUBB4ATUBB | |
| SCHEMBL1399248 | 0.84 | IFNAR1 (0.50) | HTR2ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399200 | 0.83 | HTR1A (0.64) | MEN1KMT2AGPR84HTR2ATUBB4A | |
| SCHEMBL1399176 | 0.83 | SLC6A4 (0.61) | GPR84HTR2ATUBB4ATUBBTUBA3C | |
| SCHEMBL1399348 | 0.83 | IDO1 (0.60) | GPR84TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399539 | 0.83 | IDO1 (0.60) | MEN1POLBKMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |