Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247382 | 0.92 | MET (0.67) | METMEN1KMT2AHDAC1POLB | |
| SCHEMBL13994577 | 0.91 | MET (0.55) | METHDAC1 | |
| SCHEMBL15417145 | 0.90 | MET (0.54) | METHDAC1 | |
| SCHEMBL13994271 | 0.87 | MET (0.62) | METMEN1KMT2APOLB | |
| SCHEMBL13247383 | 0.87 | MET (0.65) | METMEN1KMT2AHDAC1 | |
| SCHEMBL13247385 | 0.87 | MET (0.65) | METMEN1KMT2AHDAC1 | |
| SCHEMBL13994352 | 0.87 | MET (0.51) | METMEN1KMT2AHDAC1POLB | |
| SCHEMBL13247639 | 0.85 | MET (0.69) | METMEN1KMT2AHDAC1POLB | |
| SCHEMBL13994272 | 0.84 | MET (0.62) | METMEN1KMT2APOLB | |
| SCHEMBL13247084 | 0.84 | MET (0.68) | METMEN1KMT2AHDAC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008145243-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | WO | disclosed |