Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13994577 | 0.98 | MET (0.55) | METHDAC1 | |
| SCHEMBL13247316 | 0.92 | MET (0.64) | METHDAC1 | |
| SCHEMBL13994268 | 0.90 | MET (0.56) | METHDAC1 | |
| SCHEMBL13247318 | 0.90 | MET (0.65) | METHDAC1 | |
| SCHEMBL15417100 | 0.88 | MET (0.54) | METHDAC1 | |
| SCHEMBL13247324 | 0.86 | MET (0.67) | METHDAC1 | |
| SCHEMBL13247342 | 0.86 | MET (0.64) | METHDAC1 | |
| SCHEMBL13994271 | 0.85 | MET (0.62) | MET | |
| SCHEMBL13994632 | 0.85 | MET (0.61) | MET | |
| SCHEMBL13247149 | 0.85 | MET (0.65) | METHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150539-B1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-12-18 | — | — | EP | disclosed |