Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084177 | 0.91 | DHFR (0.43) | DHFRALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL4079264 | 0.91 | DHFR (0.43) | DHFRALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL13995094 | 0.90 | DHFR (0.42) | DHFRALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL13995091 | 0.90 | DHFR (0.42) | DHFRALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL18272711 | 0.87 | DHFR (0.40) | DHFRMAOAMAOBALDH1A1HPGD | |
| SCHEMBL12023379 | 0.84 | ALDH1A1 (0.42) | DHFRALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL16352619 | 0.84 | ALDH1A1 (0.42) | DHFRALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL16352625 | 0.84 | ALDH1A1 (0.42) | DHFRALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL26761119 | 0.84 | ENPP1 (0.43) | DHFRALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL17935584 | 0.83 | ENPP1 (0.45) | DHFRALDH1A1HPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | ANXA2, ANXA3, ANXA1 | DHFR 3036/4885MAOA 1030/4885MAOB 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.