Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484075 | 0.79 | PDK2 (0.37) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL2484077 | 0.79 | PDK2 (0.37) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL4368315 | 0.72 | PDK2 (0.46) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL17448371 | 0.69 | PDK2 (0.41) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL19286810 | 0.69 | PDK2 (0.47) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL14394456 | 0.69 | PDK2 (0.52) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL13170237 | 0.69 | PDK2 (0.43) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL21104730 | 0.69 | PDK2 (0.43) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL23676627 | 0.67 | PDK2 (0.42) | PDK2CA1CA2CA4CA7 | |
| SCHEMBL13776925 | 0.66 | PDK2 (0.44) | PDK2CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462683-B2 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2008-12-09 | — | — | US | disclosed |
| US-20070185306-A1 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185306-A1 | Dihalide, polymer compound and method for producing the same | HSPA4L, HDHD5, MRPL21 | PDK2 2058/4885CA1 2121/4885CA2 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.