Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.56 |
| ▸ | TPH1 | P17752 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997784 | 0.82 | SLC7A5 (0.65) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL1768596 | 0.81 | SLC7A5 (0.68) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL1768600 | 0.81 | SLC7A5 (0.68) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL12337990 | 0.81 | SLC7A5 (0.59) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL6776885 | 0.81 | SLC7A5 (0.68) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL13703211 | 0.81 | SLC7A5 (0.51) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL93537 | 0.80 | SLC7A5 (0.67) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL6777440 | 0.80 | SLC7A5 (0.67) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL93538 | 0.80 | SLC7A5 (0.67) | SLC7A5TPH1PTGS1ALPIPKM | |
| SCHEMBL2310526 | 0.79 | SLC7A5 (0.83) | SLC7A5TPH1PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586988-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-9586988-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20080317670-A1 | Compositions Containing, Methods Involving, and Uses of Non-Natural Amino Acids and Polypeptides | AMBRX, INC. (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080194459-A1 | Non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, therapeutic, diagnostic, and other biotechnology uses | AMBRX, INC. (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080187491-A1 | For diagnosis, genetic engineering; post-translation modification | AMBRX, INC. (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080118464-A1 | For diagnosis, genetic engineering; post-translation modification | AMBRX, INC. (US) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080317670-A1 | Compositions Containing, Methods Involving, and Uses of Non-Natural Amino Acids and Polypeptides | PTMS, DNPEP, ANPEP | SLC7A5 244/4885TPH1 2350/4885PTGS1 4559/4885 |
| US-20080118464-A1 | For diagnosis, genetic engineering; post-translation modification | PTMS, ANPEP, AADAT | SLC7A5 336/4885TPH1 1880/4885PTGS1 3797/4885 |
| US-20080187491-A1 | For diagnosis, genetic engineering; post-translation modification | PTMS, ANPEP, AADAT | SLC7A5 336/4885TPH1 1880/4885PTGS1 3797/4885 |
| US-20080194459-A1 | Non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, therapeutic, diagnostic, and other biotechnology uses | DNPEP, ANPEP, PTMS | SLC7A5 193/4885TPH1 1725/4885PTGS1 4463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.