Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 8/20 | 0.68 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | TPH1 | P17752 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GRB2 | P62993 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776885 | 1.00 | SLC7A5 (0.68) | SLC7A5LOXL2TPH1PTGS1ALPI | |
| SCHEMBL1768600 | 1.00 | SLC7A5 (0.68) | SLC7A5LOXL2TPH1PTGS1ALPI | |
| Tyrosine SCHEMBL10321534 | 0.94 | SLC7A5 (0.71) | SLC7A5LOXL2TPH1PTGS1ALPI | |
| SCHEMBL1769570 | 0.89 | LNPEP (0.65) | SLC7A5LNPEPMAPTITGB3ITGA2B | |
| SCHEMBL1769574 | 0.89 | LNPEP (0.65) | SLC7A5LNPEPMAPTITGB3ITGA2B | |
| SCHEMBL11907060 | 0.88 | POLB (0.56) | SLC7A5LOXL2TPH1LNPEPERAP2 | |
| SCHEMBL11907057 | 0.88 | POLB (0.56) | SLC7A5LOXL2TPH1LNPEPERAP2 | |
| SCHEMBL15019652 | 0.87 | LOXL2 (0.59) | SLC7A5LOXL2LNPEPERAP2MAPT | |
| SCHEMBL15019650 | 0.87 | LOXL2 (0.59) | SLC7A5LOXL2LNPEPERAP2MAPT | |
| SCHEMBL2692900 | 0.84 | LDHA (0.62) | SLC7A5LOXL2MAPTCYP4A11TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287138-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | MERCK SHARP & DOHME LLC | 2024-08-29 | — | — | US | disclosed |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| US-11629171-B2 | Beta-hairpin peptidomimetics | SPEXIS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| CN-115093463-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3201219-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3201218-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-03 | — | — | EP | disclosed |
| CN-105324390-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-10-19 | — | — | CN | disclosed |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | SPEXIS AG (CH) | 2021-09-16 | — | — | US | disclosed |
| CN-105849119-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-01-19 | — | — | CN | disclosed |
| EP-3280723-B1 | BACKBONE-CYCLIZED PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-01-06 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| CN-1152338-A | Streptogramines and method for preparing same by mutasynthesis | RHONE POULENC RORER SA (FR) | 1997-06-18 | — | — | CN | disclosed |
| EP-0770132-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | Aventis Pharma S.A. (FR) | 1997-05-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| WO-1996001901-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | RHONE-POULENC RORER S.A. (FR) | 1996-01-25 | — | — | WO | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287138-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | TNF, TNFRSF1A, CD40 | SLC7A5 3196/4885LOXL2 4370/4885TPH1 1107/4885 |
| US-11629171-B2 | Beta-hairpin peptidomimetics | POLL, POLQ, HBZ | SLC7A5 1303/4885LOXL2 4201/4885TPH1 4467/4885 |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, POLQ, POLM | SLC7A5 1534/4885LOXL2 3559/4885TPH1 4654/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | SLC7A5 3020/4885LOXL2 4802/4885TPH1 3644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.