SCHEMBL13998640

SCHEMBL13998640

Cc1cc(C(=O)Nc2c(C)cc(Cl)cc2C(=O)NC(C)(C)C)n(-c2ncccc2Cl)n1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
MALT1 Q9UDY8 1/20 0.37
MEN1 O00255 2/20 0.36
F10 P00742 7/20 0.36
ANO1 Q5XXA6 2/20 0.36
DHODH Q02127 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028762 0.91 DHODH (0.43) ALDH1A1MALT1F10ANO1DHODH
SCHEMBL12528142 0.90 KMT2A (0.40) KMT2AMALT1MEN1F10DHODH
SCHEMBL10028761 0.90 KDM4E (0.37) KMT2AALDH1A1MALT1MEN1F10
SCHEMBL29039009 0.89 ANO1 (0.35) MALT1ANO1DHODH
SCHEMBL29370423 0.87 ANO1 (0.34) MALT1ANO1DHODH
SCHEMBL15556113 0.87 ANO1 (0.34) MALT1ANO1DHODH
SCHEMBL12936147 0.87 KMT2A (0.38) KMT2AMALT1MEN1F10DHODH
SCHEMBL12911694 0.87 TSHR (0.39) KMT2AALDH1A1GAAMALT1MEN1
SCHEMBL12113183 0.87 DHODH (0.34) MALT1F10ANO1DHODH
SCHEMBL12528144 0.86 F10 (0.42) KMT2AMALT1MEN1F10DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1686857-B1 COMBINATION OF ACTIVE SUBSTANCES WITH INSECTICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2008-12-10 EP disclosed