SCHEMBL12936147

SCHEMBL12936147

Cc1cc(C(=O)Nc2c(C)cc(Cl)cc2C(=O)NC(C)C)n(-c2ncccc2Cl)n1

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.38
MALT1 Q9UDY8 1/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
RECQL P46063 1/20 0.36
F10 P00742 4/20 0.36
DHODH Q02127 1/20 0.36
CNR1 P21554 1/20 0.35
TSHR P16473 1/20 0.35
NTRK1 P04629 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782483 0.93 MALT1 (0.37) KMT2AMALT1MAPTHPGDRECQL
SCHEMBL11888055 0.91 HPGD (0.35) KMT2AMALT1MEN1MAPTHPGD
SCHEMBL16502008 0.91 PDE4B (0.37) KMT2AMALT1MAPTHPGDRECQL
SCHEMBL782232 0.91 DHODH (0.43) KMT2AMALT1MAPTHPGDRECQL
SCHEMBL12528142 0.90 KMT2A (0.40) KMT2AMALT1MEN1F10DHODH
SCHEMBL672741 0.89 PDE4B (0.36) KMT2AMALT1MEN1MAPTF10
SCHEMBL16181542 0.89 MALT1 (0.35) MALT1MAPTHPGDRECQLDHODH
SCHEMBL14619128 0.89 MALT1 (0.35) KMT2AMALT1MAPTHPGDRECQL
SCHEMBL12559349 0.88 ALDH1A1 (0.38) KMT2AMALT1MEN1F10DHODH
SCHEMBL12911694 0.87 TSHR (0.39) KMT2AMALT1MEN1F10DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1699290-B1 INSECTICIDAL ACTIVE SUBSTANCE COMBINATIONS CONTAINING ANTHRANILIC ACID AMIDES AND AT LEAST ONE OTHER INSECTICIDE BAYER CROPSCIENCE AG (DE) 2011-02-16 EP disclosed
EP-1686857-B1 COMBINATION OF ACTIVE SUBSTANCES WITH INSECTICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2008-12-10 EP disclosed