SCHEMBL29039009

SCHEMBL29039009

Cc1cc(Cl)cc(C(=O)NC(C)(C)C)c1NC(=O)c1cc(CF)nn1-c1ncccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ANO1 Q5XXA6 9/20 0.35
MALT1 Q9UDY8 2/20 0.35
DHODH Q02127 1/20 0.34
NTRK1 P04629 1/20 0.33
TRPV1 Q8NER1 5/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12113183 0.91 DHODH (0.34) ANO1MALT1DHODHCNR1CNR2
SCHEMBL15255576 0.91 ACKR3 (0.36) ANO1MALT1DHODHNTRK1
SCHEMBL13998640 0.89 KMT2A (0.38) ANO1MALT1DHODH
SCHEMBL15556113 0.89 ANO1 (0.34) ANO1MALT1DHODHNTRK1CNR1
SCHEMBL29370423 0.89 ANO1 (0.34) ANO1MALT1DHODHNTRK1CNR1
SCHEMBL16181542 0.88 MALT1 (0.35) MALT1DHODHNTRK1TRPV1CNR1
SCHEMBL10028761 0.87 KDM4E (0.37) MALT1DHODHTRPV1
SCHEMBL12113225 0.87 MALT1 (0.33) ANO1MALT1DHODHNTRK1TRPV1
SCHEMBL685544 0.87 DHODH (0.33) ANO1MALT1DHODHNTRK1TRPV1
SCHEMBL10028762 0.87 DHODH (0.43) ANO1MALT1DHODHTRPV1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116234444-A Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof 皮埃企业有限公司 2023-06-06 CN claimed