Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 19/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 19/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 19/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13999215 | 1.00 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL13999214 | 0.91 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL5101979 | 0.91 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL5101975 | 0.91 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL5101829 | 0.83 | ADRA1A (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5112041 | 0.83 | ADRA1A (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5101822 | 0.83 | ADRA1A (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL13999208 | 0.82 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5110677 | 0.82 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5101641 | 0.78 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470711-B2 | Piperidinyl substituted cyclohexane-1,4-diamines | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-30 | — | — | US | disclosed |
| US-7470711-B2 | Piperidinyl substituted cyclohexane-1,4-diamines | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-30 | — | — | US | disclosed |