Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.46 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BMX | P51813 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13999908 | 0.94 | ESR1 (0.44) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14363297 | 0.93 | ESR2 (0.46) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL2604842 | 0.91 | ESR1 (0.56) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14000009 | 0.91 | ESR1 (0.40) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL19309092 | 0.91 | ESR1 (0.43) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL26344616 | 0.90 | ESR1 (0.44) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14363367 | 0.90 | SIRT2 (0.41) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL124880 | 0.90 | ESR1 (0.58) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15696436 | 0.90 | ESR1 (0.51) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL29511658 | 0.90 | ESR1 (0.58) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000464-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
| US-20070267970-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| US-20070267970-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070267970-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | NUDC, NUDT1, SLC43A1 | ESR1 1029/4885ESR2 2015/4885GRIA1 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.