Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.65 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.65 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.65 |
| ▸ | RRM1 | P23921 | 1/20 | 0.59 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.57 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169779 | 0.93 | GNAI3 (0.65) | GNAI3GNAO1GNAI1RRM1SIRT6 | |
| SCHEMBL20169781 | 0.93 | GNAI3 (0.65) | GNAI3GNAO1GNAI1RRM1SIRT6 | |
| SCHEMBL20169776 | 0.93 | GNAI3 (0.65) | GNAI3GNAO1GNAI1RRM1SIRT6 | |
| SCHEMBL14627818 | 0.93 | DPP7 (0.56) | GNAI3GNAO1GNAI1RRM1SIRT6 | |
| SCHEMBL20073076 | 0.92 | GNAI3 (0.62) | GNAI3GNAO1GNAI1RRM1SIRT6 | |
| SCHEMBL28328772 | 0.90 | DPP7 (0.62) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL21467378 | 0.88 | DPP7 (0.65) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL23073481 | 0.86 | GNAI3 (0.55) | GNAI3GNAO1GNAI1RRM1SIRT6 | |
| SCHEMBL26756576 | 0.86 | DPP7 (0.65) | GNAI3GNAO1GNAI1RRM1SIRT6 | |
| SCHEMBL14874696 | 0.86 | GNAI3 (0.58) | GNAI3GNAO1GNAI1RRM1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445641-B1 | Biomaterials modified with superoxide dismutase mimics | PHARMACIA CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |