SCHEMBL26756576

SCHEMBL26756576

CCCCCNC(=O)[C@@H](C)CC[C@H](C)C(=O)NCCN

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.65
▸ RRM1 P23921 1/20 0.63
▸ GNAI3 P08754 1/20 0.59
▸ GNAO1 P09471 1/20 0.59
▸ GNAI1 P63096 1/20 0.59
▸ SIRT6 Q8N6T7 1/20 0.54
▸ SIRT1 Q96EB6 1/20 0.54
▸ CNR1 P21554 1/20 0.49
▸ MMP8 P22894 1/20 0.47
▸ EPHX1 P07099 7/20 0.47
▸ TLR2 O60603 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20169781 0.90 GNAI3 (0.65) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL20169779 0.90 GNAI3 (0.65) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL20169776 0.90 GNAI3 (0.65) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL21467378 0.87 DPP7 (0.65) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL14001785 0.86 GNAI3 (0.65) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL14627818 0.86 DPP7 (0.56) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL24072535 0.85 DPP7 (0.58) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL14874696 0.85 GNAI3 (0.58) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL14138765 0.85 DPP7 (0.58) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL23430583 0.85 DPP7 (0.58) DPP7RRM1GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11813358-B2 Lipid nanodisc formation by polymers having a pendant hydrophobic group REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11813358-B2 Lipid nanodisc formation by polymers having a pendant hydrophobic group PLIN3, ABHD16A, HDLBP DPP7 3442/4885RRM1 1046/4885GNAI3 1559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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