Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | NEK4 | P51957 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27009309 | 0.77 | CYP26B1 (0.40) | ACHECHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL11640241 | 0.76 | BACE1 (0.44) | LMNAOPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL2084258 | 0.74 | MAOB (0.39) | ACHECHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL27579512 | 0.72 | HTR2C (0.37) | ACHECHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL30717245 | 0.69 | CHRNA1 (0.53) | ACHECHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL8064830 | 0.68 | BACE1 (0.42) | SLC6A2SLC6A3LMNAOPRM1OPRK1 | |
| SCHEMBL17028535 | 0.68 | ACHE (0.48) | ACHECHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL23714594 | 0.68 | CHRNA1 (0.47) | ACHECHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL3786132 | 0.68 | SMN1; SMN2 (0.55) | ACHECHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL16029802 | 0.68 | HDAC4 (0.50) | ACHECHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446229-B2 | Bicyclic cannabinoids | UNIVERSITY OF CONNECTICUT (US) | 2008-11-04 | — | — | US | disclosed |
| US-7446229-B2 | Bicyclic cannabinoids | UNIVERSITY OF CONNECTICUT (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070135388-A1 | Novel Bicyclic Cannabinoids | UNIVERSITY OF CONNECTICUT | 2007-06-14 | — | — | US | disclosed |
| US-20070135388-A1 | Novel Bicyclic Cannabinoids | UNIVERSITY OF CONNECTICUT | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135388-A1 | Novel Bicyclic Cannabinoids | CNR2, CNR1, GPR18 | ACHE 1302/4885CHRNA1 217/4885CHRNG 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.