Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | ACR | P10323 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25500897 | 0.87 | PRSS1 (0.51) | PRSS1ACRKMT2AMEN1HPGD | |
| SCHEMBL8930157 | 0.87 | PRSS1 (0.69) | PRSS1ACRKMT2AMEN1HPGD | |
| SCHEMBL2741098 | 0.87 | PRSS1 (0.69) | PRSS1ACRKMT2AMEN1HPGD | |
| SCHEMBL9663961 | 0.87 | PRSS1 (0.69) | PRSS1ACRKMT2AMEN1HPGD | |
| SCHEMBL1101878 | 0.87 | PRSS1 (0.69) | PRSS1ACRKMT2AMEN1HPGD | |
| SCHEMBL8929987 | 0.87 | PRSS1 (0.69) | PRSS1ACRKMT2AMEN1HPGD | |
| SCHEMBL12473427 | 0.86 | LMNA (0.60) | PRSS1ACRKMT2ALMNAGBA1 | |
| SCHEMBL19599191 | 0.86 | PRSS1 (0.56) | PRSS1ACRKMT2AMEN1HPGD | |
| SCHEMBL20010786 | 0.86 | CES2 (0.59) | TDP1NPC1RAB9ATRPV1EPHX2 | |
| SCHEMBL14145709 | 0.84 | AURKA (0.49) | PRSS1ACRNPC1RAB9ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029127-B1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-7452575-B2 | Liquid crystal medium and liquid crystal display with a highly twisted structure | MERCK PATENT GMBH (DE) | 2008-11-18 | — | — | US | disclosed |