Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891891 | 0.91 | HTR6 (0.50) | HTR6CA1CA2GRM4RAPGEF4 | |
| SCHEMBL21806794 | 0.88 | CA1 (0.54) | HTR6CA1CA2GRM4RAPGEF4 | |
| SCHEMBL4227579 | 0.85 | HTR6 (0.52) | HTR6CA1CA2GRM4RAPGEF4 | |
| SCHEMBL4223924 | 0.85 | HTR6 (0.52) | HTR6CA1CA2GRM4RAPGEF4 | |
| SCHEMBL13891892 | 0.82 | HTR6 (0.50) | HTR6CA1CA2GRM4RAPGEF4 | |
| SCHEMBL4521506 | 0.81 | CA1 (0.54) | HTR6CA1CA2GRM4RAPGEF4 | |
| SCHEMBL18920680 | 0.81 | HTR6 (0.52) | HTR6CA1CA2GRM4PKM | |
| SCHEMBL14726924 | 0.80 | CA1 (0.53) | HTR6CA1CA2GRM4RAPGEF4 | |
| SCHEMBL13891894 | 0.79 | HTR6 (0.47) | HTR6CA1CA2GRM4RAPGEF4 | |
| SCHEMBL14005233 | 0.78 | HTR6 (0.46) | HTR6CA1CA2GRM4RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446186-B2 | Pyrroles substituted by oligonucleotides | BIOMERIEUX (FR) | 2008-11-04 | — | — | US | disclosed |
| US-7446186-B2 | Pyrroles substituted by oligonucleotides | BIOMERIEUX (FR) | 2008-11-04 | — | — | US | disclosed |