Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28748262 | 0.89 | CA1 (0.43) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL27572536 | 0.88 | CA1 (0.45) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL4227579 | 0.86 | HTR6 (0.52) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL4521506 | 0.81 | CA1 (0.54) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL14005226 | 0.78 | HTR6 (0.52) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL4223924 | 0.78 | HTR6 (0.52) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL18920680 | 0.77 | HTR6 (0.52) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL18920634 | 0.76 | ALDH1A1 (0.47) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL13891891 | 0.76 | HTR6 (0.50) | HTR6CA1CA2GRM4ALDH1A1 | |
| SCHEMBL13891892 | 0.76 | HTR6 (0.50) | HTR6CA1CA2GRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446186-B2 | Pyrroles substituted by oligonucleotides | BIOMERIEUX (FR) | 2008-11-04 | — | — | US | disclosed |