Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597447 | 0.87 | CYP2C19 (0.59) | POLBCYP2C19HTTMAPK1CYP3A4 | |
| SCHEMBL2789865 | 0.83 | CYP2C19 (0.58) | POLBCYP2C19HTTCYP3A4CYP2D6 | |
| SCHEMBL2733465 | 0.82 | POLB (0.60) | POLBCYP2C19HTTMAPK1KMT2A | |
| SCHEMBL7165398 | 0.81 | POLB (0.63) | POLBCYP2C19HTTMAPK1KMT2A | |
| SCHEMBL3373963 | 0.81 | POLB (0.63) | POLBCYP2C19HTTMAPK1KMT2A | |
| SCHEMBL9570331 | 0.81 | CYP2C19 (0.56) | POLBCYP2C19HTTMAPK1CYP3A4 | |
| SCHEMBL7973895 | 0.80 | CYP11B1 (0.55) | POLBCYP2C19THRBFNTAFNTB | |
| SCHEMBL28026195 | 0.79 | CYP2C19 (0.59) | POLBCYP2C19MAPK1CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL28085228 | 0.78 | CYP2C19 (0.56) | POLBCYP2C19HTTMAPK1CYP3A4 | |
| SCHEMBL11161541 | 0.77 | CYP2C19 (0.54) | POLBCYP2C19HTTMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-27 | — | — | US | disclosed |
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-27 | — | — | US | disclosed |
| WO-2007034251-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293745-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | POLB 4214/4885CYP2C19 3078/4885HTT 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.