Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092968 | 0.84 | HPGDS (0.49) | CYP2C19PTGDR2POLBLMNATSHR | |
| SCHEMBL14005999 | 0.83 | POLB (0.66) | CYP2C19CYP3A4CYP2D6POLBFNTA | |
| Water SCHEMBL11097766 | 0.82 | HPGDS (0.48) | CYP2C19PTGDR2POLBLMNATSHR | |
| SCHEMBL9597447 | 0.80 | CYP2C19 (0.59) | CYP2C19CYP3A4CYP2D6POLBFNTA | |
| SCHEMBL9570331 | 0.80 | CYP2C19 (0.56) | CYP2C19CYP3A4CYP2D6POLBFNTA | |
| SCHEMBL1713531 | 0.77 | SMN1; SMN2 (0.55) | CYP2C19PTGDR2CYP3A4CYP2D6POLB | |
| SCHEMBL28026195 | 0.75 | CYP2C19 (0.59) | CYP2C19CYP3A4CYP2D6POLBLMNA | |
| Hydrochloric Acid SCHEMBL28085228 | 0.75 | CYP2C19 (0.56) | CYP2C19CYP3A4CYP2D6POLBFNTA | |
| SCHEMBL5327448 | 0.74 | AR (0.53) | PTGDR2POLBLMNAKDM4EHTT | |
| SCHEMBL11161541 | 0.74 | CYP2C19 (0.54) | CYP2C19CYP3A4CYP2D6POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691859-B2 | Prenyl transferase inhibitors | IPSEN PHARMA S.A.S. (FR) | 2010-04-06 | — | — | US | disclosed |
| EP-1382607-B1 | Prenyl transferase inhibitors | IPSEN PHARMA (FR) | 2009-08-19 | — | — | EP | disclosed |
| US-20080176835-A1 | Prenyl Transferase Inhibitors | BIOMEASURE, INCORPORATED | 2008-07-24 | — | — | US | disclosed |
| US-7361656-B2 | Prenyl transferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2008-04-22 | — | — | US | disclosed |
| US-7084135-B1 | Prenyl transferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, SAS (FR) | 2006-08-01 | — | — | US | disclosed |
| US-20060142275-A1 | Prenyl transferase inhibitors | IPSEN PHARMA S.A.S. (FR) | 2006-06-29 | — | — | US | disclosed |
| EP-1140942-B1 | PRENYL TRANSFERASE INHIBITORS | CONSEILS DE RECH SET D APPLIC (FR) | 2004-03-10 | — | — | EP | disclosed |
| EP-1382607-A2 | Prenyl transferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176835-A1 | Prenyl Transferase Inhibitors | FNTA, FNTB, RCE1 | CYP2C19 1880/4885PTGDR2 2573/4885CYP3A4 944/4885 |
| US-20060142275-A1 | Prenyl transferase inhibitors | FNTA, FNTB, RCE1 | CYP2C19 1880/4885PTGDR2 2573/4885CYP3A4 944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.