Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057437 | 0.85 | POLB (0.45) | POLBHTTMAPK1HPGDSKMT2A | |
| SCHEMBL6973556 | 0.84 | POLB (0.47) | POLBHTTMAPK1KMT2AALDH1A1 | |
| SCHEMBL11092968 | 0.83 | HPGDS (0.49) | POLBHTTHPGDSALDH1A1PDE6D | |
| SCHEMBL14005999 | 0.82 | POLB (0.66) | POLBHTTMAPK1KMT2AALDH1A1 | |
| Water SCHEMBL11097766 | 0.82 | HPGDS (0.48) | POLBHTTHPGDSKMT2AALDH1A1 | |
| SCHEMBL3373963 | 0.80 | POLB (0.63) | POLBHTTMAPK1KMT2AALDH1A1 | |
| SCHEMBL7165398 | 0.80 | POLB (0.63) | POLBHTTMAPK1KMT2AALDH1A1 | |
| SCHEMBL11099706 | 0.78 | AR (0.47) | POLBMAPK1HPGDSKMT2AALDH1A1 | |
| SCHEMBL650440 | 0.77 | TSHR (0.58) | POLBALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL4418297 | 0.76 | HPGDS (0.51) | POLBHPGDSALDH1A1PDE6DALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635619-A1 | EPOXY-THIOL COMPOSITIONS WITH IMPROVED STABILITY | Henkel Ireland Limited (DE) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059558-A1 | EPOXY-THIOL COMPOSITIONS WITH IMPROVED STABILITY | LOCTITE (R&D) LIMITED (IE) | 2012-05-10 | — | — | WO | disclosed |