Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 10/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14006277 | 0.89 | HTR1A (0.59) | CACNA1GCHRNA7KCNH2 | |
| SCHEMBL14006221 | 0.87 | CACNA1G (0.71) | CACNA1GTP53CHRNA7 | |
| SCHEMBL14006298 | 0.86 | HDAC3 (0.54) | CHRNA7KCNH2 | |
| SCHEMBL14006149 | 0.86 | CACNA1G (0.52) | CACNA1GCHRNA7KCNH2 | |
| SCHEMBL14006278 | 0.85 | CACNA1G (0.70) | CACNA1GTP53CHRNA7 | |
| SCHEMBL14006219 | 0.85 | CACNA1G (0.70) | CACNA1GTP53CHRNA7 | |
| SCHEMBL14006291 | 0.84 | EPHX2 (0.58) | CHRNA7KCNH2 | |
| SCHEMBL2055592 | 0.82 | CHRNA7 (0.59) | CHRNA7KCNH2 | |
| SCHEMBL14006146 | 0.81 | CHRNA7 (0.51) | CHRNA7KCNH2 | |
| SCHEMBL14006150 | 0.81 | CHRNA7 (0.53) | CHRNA7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | CHRNA7, CHRNA5, CHRNA1 | CACNA1G 324/4885TP53 3541/4885CHRNA7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.