Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400940 | 0.89 | S1PR1 (0.40) | PTGER1PTGER4PTGER3PTGER2PPARA | |
| SCHEMBL69550 | 0.86 | CYP3A4 (0.37) | ALOX15CYP2D6CYP2C19 | |
| SCHEMBL69837 | 0.84 | AKR1C3 (0.44) | SMN1; SMN2 | |
| SCHEMBL69838 | 0.84 | AKR1C3 (0.44) | SMN1; SMN2 | |
| SCHEMBL67070 | 0.81 | RXRA (0.44) | CYP2C19LTB4R2PPARG | |
| SCHEMBL1400849 | 0.80 | PPARG (0.37) | PTGER1PTGER4PTGER3PTGER2PPARA | |
| SCHEMBL68946 | 0.78 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2LTB4R2 | |
| SCHEMBL70089 | 0.78 | CYP1A2 (0.38) | PPARACYP2C19PPARG | |
| SCHEMBL67082 | 0.75 | PPARG (0.42) | ITGB3ITGA2BSMN1; SMN2PTGESALOX5 | |
| SCHEMBL1750047 | 0.74 | PPARA (0.42) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-B1 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-03-02 | — | — | EP | claimed |