Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198183 | 0.86 | RXRA (0.41) | PPARGPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL68526 | 0.83 | PPARG (0.36) | PPARGPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL1400847 | 0.83 | PTGER1 (0.34) | PTGER1PTGER4PTGER3PTGER2PPARD | |
| SCHEMBL5198621 | 0.81 | KDM4E (0.43) | PPARGPPARAPPARD | |
| SCHEMBL1400797 | 0.80 | PDK2 (0.32) | PTGESALOX5PPARDHTR2CSLC6A4 | |
| SCHEMBL1400796 | 0.80 | PDK2 (0.32) | PTGESALOX5PPARDHTR2CSLC6A4 | |
| SCHEMBL1400699 | 0.80 | ALOX15 (0.36) | PPARGPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL67070 | 0.72 | RXRA (0.44) | PPARGPTPN1S1PR1S1PR3S1PR5 | |
| SCHEMBL2843431 | 0.70 | HTR2C (0.43) | HTR2CSLC6A4 | |
| SCHEMBL67388 | 0.69 | TDP1 (0.40) | PPARDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-B1 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-03-02 | — | — | EP | disclosed |