Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.62 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14007009 | 0.86 | DPP4 (0.65) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL8491016 | 0.85 | DPP4 (0.61) | DPP4CYP3A4DPP7DPP9DPP8 | |
| SCHEMBL24244598 | 0.83 | DPP4 (0.79) | DPP4CYP3A4DPP7DPP9DPP8 | |
| SCHEMBL28434489 | 0.83 | DPP4 (0.79) | DPP4CYP3A4DPP7DPP9DPP8 | |
| SCHEMBL25840236 | 0.82 | DPP4 (0.77) | DPP4CYP3A4DPP7DPP9DPP8 | |
| SCHEMBL4699518 | 0.81 | DPP4 (0.68) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL4699986 | 0.81 | DPP4 (0.68) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL22055971 | 0.81 | DPP4 (0.65) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL4407412 | 0.81 | DPP4 (0.64) | DPP4CYP3A4DPP7DPP9DPP8 | |
| SCHEMBL21985110 | 0.80 | DPP4 (0.88) | DPP4CYP3A4DPP7DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275086-A1 | Dpp-Iv Inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2008-11-06 | — | — | US | disclosed |
| US-20080275086-A1 | Dpp-Iv Inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275086-A1 | Dpp-Iv Inhibitors | DPP4, DPP7, DPP3 | DPP4 1/4885CYP3A4 101/4885DPP7 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.