Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 6/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281714 | 0.78 | MAOA (0.57) | MAOAMAOBPRKCIDRD2DRD1 | |
| SCHEMBL29442640 | 0.78 | MAOA (0.57) | MAOAMAOBPRKCIDRD2DRD1 | |
| SCHEMBL3451975 | 0.77 | CYP1A2 (0.78) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL29405718 | 0.77 | CYP1A2 (0.68) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL392290 | 0.77 | CYP1A2 (0.68) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL29973107 | 0.77 | CYP1A2 (0.68) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL755928 | 0.77 | CYP1A2 (0.68) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL627219 | 0.77 | CYP1A2 (0.77) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL69484 | 0.77 | CYP1A2 (0.77) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL29364786 | 0.77 | CYP1A2 (0.77) | CYP1A2ESR1ESR2CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280935-A1 | Process to Prepare Camptothecin Derivatives | CHATHAM BIOTEC, LIMITED (CA) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280935-A1 | Process to Prepare Camptothecin Derivatives | TOP1, TOP2A, SI | CYP1A2 214/4885MAOA 3244/4885MAOB 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.